Modelling amyotrophic lateral sclerosis in rodents.

Abstract excerpt

The efficient study of human disease requires the proper tools, one of the most crucial of which is an accurate animal model that faithfully recapitulates the human condition. The study of amyotrophic lateral sclerosis (ALS) is no exception. Although the majority of ALS cases are considered sporadic, most animal models of this disease rely on genetic mutations identified in familial cases. Over the past decade,...

Topics

• Amyotrophic Lateral Sclerosis
• Animals
• Disease Models, Animal
• Humans
• Mutation
• Rodentia