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B-cell-depletion reverses dysbiosis of the microbiome in multiple sclerosis patients

8 Mar 2022

Abstract excerpt

To elucidate cross-sectional patterns and longitudinal changes of oral and stool microbiota in multiple sclerosis (MS) patients and the effect of B-cell depletion. We conducted an observational, longitudinal clinical cohort study analysing four timepoints over 12 months in 36 MS patients, of whom 22 initiated B-cell depleting therapy with ocrelizumab and a healthy control group. For microbiota analysis of the...

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PMID: 35260584
DOI: 10.1038/s41598-022-07336-8

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