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Prognostic signature for hepatocellular carcinoma based on 4 pyroptosis-related genes

28 Jul 2022

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is a cancer with a poor prognosis. Many recent studies have suggested that pyroptosis is important in tumour progression. However, the role of pyroptosis-related genes (PRGs) in HCC remains unclear. MATERIALS AND METHODS: We identified differentially expressed PRGs in tumours versus normal tissues. Through univariate, LASSO, and multivariate Cox regression analyses, a...

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PMID: 35902905
DOI: 10.1186/s12920-022-01322-9

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