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Distribution of rotavirus genotypes in Japan from 2015 to 2018: Diversity in genotypes before and after introduction of rotavirus vaccines.

Vaccine - 13 May 2020

Hoque Sheikh Ariful, Khandoker Nusrat, Thongprachum Aksara, Khamrin Pattara, Takanashi Sayaka, Okitsu Shoko, Nishimura Shuichi, Kikuta Hideaki, Yamamoto Atsuko, Sugita Kumiko, Baba Tsuneyoshi, Kobayashi Masaaki, Hayakawa Satoshi, Mizuguchi Masashi, Maneekarn Niwat, Ushijima Hiroshi

Abstract excerpt

BACKGROUND: Diversity in group A rotavirus (RVA) strains after introduction of RV-vaccines remains an emerging concern worldwide. In this study, we investigated the prevalence and distribution of RVA genotypes in Japanese children with acute gastroenteritis (AGE) from 2015 to 2018. In addition, a comparison of the genotypes in pre-vaccination (2006-2012) and post-vaccination (2012-2018) periods was conducted to...

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PMID: 32307276
DOI: 10.1016/j.vaccine.2020.03.061

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