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Article

Modulation of miR-204 Expression during Chondrogenesis

15 Feb 2022

Abstract excerpt

RUNX2 and SOX9 are two pivotal transcriptional regulators of chondrogenesis. It has been demonstrated that RUNX2 and SOX9 physically interact; RUNX2 transactivation may be inhibited by SOX9. In addition, RUNX2 exerts reciprocal inhibition on SOX9 transactivity. Epigenetic control of gene expression plays a major role in the alternative differentiation fates of stem cells; in particular, it has been reported that...

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PMID: 35216245
DOI: 10.3390/ijms23042130

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