A Review of Circulating Tumor DNA in the Diagnosis and Monitoring of Esophageal Cancer.

Abstract excerpt

Circulating tumor DNA (ctDNA) is a type of cell-free DNA released by tumor cells after necrosis and apoptosis, and it can be actively secreted by tumor cells. Since ctDNA is derived from various tumor sites, it can provide far more comprehensive genomic and epigenomic information than a single-site biopsy. Therefore, ctDNA can overcome tumor heterogeneity, which is the major limitation of a traditional tissue...

Topics

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• Biomarkers, Tumor
• Cell-Free Nucleic Acids
• Circulating Tumor DNA
• DNA Mutational Analysis
• Esophageal Neoplasms