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Article

Clinical Significance of Hepsin and Underlying Signaling Pathways in Prostate Cancer

25 Jan 2022

Abstract excerpt

The hepsin gene encodes a type II transmembrane serine protease. Previous studies have shown the overexpression of hepsin in prostate cancer, and the dysregulation of hepsin promotes cancer cell proliferation, migration, and metastasis in vitro and in vivo. The review incorporated with our work showed that hepsin expression levels were specifically increased in prostate cancer, and higher expression in metastatic...

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PMID: 35204704
DOI: 10.3390/biom12020203

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