Modifying the maternal microbiota alters the gut–brain metabolome and prevents emotional dysfunction in the adult offspring of obese dams

Abstract excerpt

Significance Maternal obesity is a growing public health concern and is linked to an increased risk of neurodevelopmental and psychiatric disorders in humans. Despite accumulating evidence for the important role maternal microbes play during gestation and nursing, the longitudinal effect of maternal nutrition on offspring metabolism across the gut–brain axis at different ages remains unexplored. We provide...

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