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Article

Three Pediatric Siblings With CADASIL.

Pediatric neurology - 1 Apr 2022

Torres Marcela, Hamby Tyler, Tilley Jo, Schenk Allyson, Acosta Fernando, Kurjee Nehel, Russell Katherine

Abstract excerpt

BACKGROUND: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a congenital small vessel disease of the brain due to NOTCH3 gene mutations. Although adult-onset CADASIL is well documented, more cases are being described within the pediatric population. We describe three siblings with NOTCH3 mutations with various symptomatic presentations of early-onset CADASIL...

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Identifiers

PMID: 35196639
DOI: 10.1016/j.pediatrneurol.2022.01.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Three Pediatric Siblings With CADASIL.PMID 35196639Read ↗

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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy revisitedSemantic proximity Read ↗

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