Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progesterone Inhibits the Establishment of Activation-Associated Chromatin During TH1 Differentiation

2 Feb 2022

Abstract excerpt

TH1-mediated diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) improve during pregnancy, coinciding with increasing levels of the pregnancy hormone progesterone (P4), highlighting P4 as a potential mediator of this immunomodulation. Here, we performed detailed characterization of how P4 affects the chromatin and transcriptomic landscape during early human TH1 differentiation, utilizing both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Reproductive System and Pregnancy
Share to T-cell and Retrovirus Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35185927
DOI: 10.3389/fimmu.2022.835625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progesterone Inhibits the Establishment of Activation-Associated Chromatin During TH1 DifferentiationPMID 35185927Read ↗

Progesterone specifically dampens disease-associated T <sub>H</sub> 1- and T <sub>H</sub> 17-related immune responses during T cell activation <i>in vitro</i>Semantic proximity Read ↗

Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During PregnancySemantic proximity Read ↗

Progesterone Receptor Transcriptome and Cistrome in Decidualized Human Endometrial Stromal CellsSemantic proximity Read ↗

Progesterone‐Regulated Endometrial Factors Controlling ImplantationSemantic proximity Read ↗

Roles of Progesterone Receptor A and B Isoforms During Human Endometrial DecidualizationSemantic proximity Read ↗

Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial RegulatorsSemantic proximity Read ↗

Human endometrial stromal cell decidualization requires transcriptional reprogramming by PLZF†Semantic proximity Read ↗

Transcriptomic Changes During the Pre-Receptive to Receptive Transition in Human Endometrium Detected by RNA-SeqSemantic proximity Read ↗

The Promyelocytic Leukemia Zinc Finger Transcription Factor Is Critical for Human Endometrial Stromal Cell DecidualizationSemantic proximity Read ↗

CFP1 governs uterine epigenetic landscapes to intervene in progesterone responses for uterine physiology and suppression of endometriosisSemantic proximity Read ↗

Progesterone attenuates Th17-cell pathogenicity in autoimmune uveitis via Id2/Pim1 axisSemantic proximity Read ↗

Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.