Article
Complete Bone Marrow Necrosis with Charcot-Leyden Crystals Caused by Myeloid Neoplasm with Mutated NPM1 and TET2.
Internal medicine (Tokyo, Japan) - 1 Nov 2022
Saito Kenki, Sato Takayuki, Notohara Kenji, Nannya Yasuhito, Ogawa Seishi, Ueda Yasunori
Abstract excerpt
Bone marrow necrosis (BMN) has various underlying diseases. In hematological malignancies, both lymphoid and myeloid neoplasms have been shown to cause BMN. Charcot-Leyden crystals (CLCs) are bipyramidal crystals that have been found in patients with immune system diseases, tumors, skin diseases, asthma, infections, and intestinal diseases. Because the combination of CLCs and acute myeloid leukemia (AML) is rare,...
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