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Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates

11 Feb 2022

Abstract excerpt

Hypertension specifically had detrimental effects on microbial translocation when age and metabolic syndrome criteria were evaluated as drivers of cardiovascular disease in a relevant nonhuman primate model. Intestinal barrier function exponentially decayed over time with chronic hypertension, and microbial translocation was confirmed by detection of more microbial genes in regional draining lymph nodes. Chronic...

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PMID: 35148233
DOI: 10.1152/ajpheart.00530.2021

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