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Article

Hypervirulent FAdV-4 infection induces activation of the NLRP3 inflammasome in chicken macrophages

31 Dec 2021

Abstract excerpt

Fowl adenovirus serotype 4 (FAdV-4) is the primary causative agent of hepatitis-hydropericardium syndrome (HHS) causing great economic losses to the world poultry industry. The exact factors responsible for the pathogenesis of hypervirulent FAdV-4 have not been completely elucidated. Hypervirulent FAdV-4 infection induces inflammatory damages in accompany with a high level of proinflammatory interleukin-1 beta...

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PMID: 35077922
DOI: 10.1016/j.psj.2021.101695

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