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Article

Performance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects.

Genetics, selection, evolution : GSE - 21 Jan 2022

Ablondi Michela, Johnsson Martin, Eriksson Susanne, Sabbioni Alberto, Viklund Åsa Gelinder, Mikko Sofia

Abstract excerpt

BACKGROUND: Warmblood fragile foal syndrome (WFFS) is a monogenetic defect caused by a recessive lethal missense point mutation in the procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 gene (PLOD1, c.2032G>A). The majority of homozygous WFFS horses are aborted during gestation. Clinical signs of affected horses include fragile skin, skin and mucosa lacerations, hyperextension of the articulations, and hematomas....

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Identifiers

PMID: 35062868
DOI: 10.1186/s12711-021-00693-4
PMCID: PMC8783495

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