Article
Successful desensitization under antihistamine suppression in a case with urticaria due to osimertinib.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners - 1 Sept 2022
Vural Solak Gürgün Tuğçe, Aksu Kurtuluş, Topel Musa, Çuhadar Erçelebi Dilek, Yeşilkaya Selma, Demir Şenay, Köycü Buhari Gözde, Koca Kalkan İlkay, Ateş Hale, Nazik Bahçecioğlu Sakine
Abstract excerpt
INTRODUCTION: Osimertinib is an approved therapy for patients with a Thr790met (T790M) mutation diagnosed with non-small cell lung cancer (NSCLC) that progresses during epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy. However, in 7-13% of patients, drug-related side effects lead to discontinuation of osimertinib treatment. In such cases, osimertinib desensitization is a treatment...
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