Article
Alpha-1 antitrypsin deficiency and risk of lung cancer in never-smokers: a multicentre case-control study.
BMC cancer - 19 Jan 2022
Tubío-Pérez Ramón Antonio, Torres-Durán María, García-Rodríguez María Esmeralda, Candal-Pedreira Cristina, Rey-Brandariz Julia, Pérez-Ríos Mónica, Barros-Dios Juan, Fernández-Villar Alberto, Ruano-Raviña Alberto
Abstract excerpt
BACKGROUND: Lung cancer (LC) is the most commonly diagnosed cancer and the leading cause of cancer-related death in both sexes worldwide. Although the principal risk factor in the western world is tobacco smoking, genetic factors, including alpha-1 antitrypsin deficiency (AATD), have been associated with increased risk. This study is the continuation of an earlier one published by the same group in 2015, aimed at...
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