Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High incidence of hypertension-mediated organ damage in a series of Chinese patients with 17α-hydroxylase deficiency.

Endocrine - 1 Apr 2022

Zhao Zhiyuan, Lu Lin, Wang Ou, Wu Xueyan, Sun Bang, Zhang Wei, Wang Xi, Mao Jiangfeng, Chen Shi, Tong Anli, Nie Min

Abstract excerpt

OBJECTIVE: To analyze the prevalence of hypertension-mediated organ damage (HMOD) and its relationship with enzyme activity of mutant CYP17A1 and other risk factors in patients with 17α-hydroxylase/17,20-lyase deficiency (17-OHD). METHODS: A total of 68 patients with 17-OHD were recruited in the Peking Union Medical College Hospital from 2003 to 2021. The incidence of hypertension and HMOD was respectively...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Hyperplasia, Congenital
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Hypokalemia

Share to Incidence

Share to Mixed Function Oxygenases

Share to Mutation

Share to Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 35032013
DOI: 10.1007/s12020-021-02966-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High incidence of hypertension-mediated organ damage in a series of Chinese patients with 17α-hydroxylase deficiency.PMID 35032013Read ↗

High incidence of hypertension-mediated organ damage in a series of Chinese patients with 17α-hydroxylase deficiencySemantic proximity Read ↗

Clinical and Genetic Characteristics of 17 α-Hydroxylase/17, 20-Lyase Deficiency: c.985_987delTACinsAA Mutation of CYP17A1 Prevalent in the Chinese Han Population.Semantic proximity Read ↗

Presentation, Diagnosis, and Follow-Up Characteristics of 17α-Hydroxylase Deficiency Cases with Exon 1-6 Deletion (Founder Mutation) in the CYP17A1Gene: 20-Year Single-Center Experience.Semantic proximity Read ↗

Novel CYP17A1 variants and functional validation in a large Chinese cohort of complete 17α-hydroxylase deficiency.Semantic proximity Read ↗

The potential Role of CYP2D6*10(c.100 C>T) Gene Polymorphism in Kidney Injury of Patients with Hypertension Complicated with Non-Elevated Cystatin C.Semantic proximity Read ↗

New, recurrent, and prevalent mutations: Clinical and molecular characterization of 26 Chinese patients with 17alpha-hydroxylase/17,20-lyase deficiency.Semantic proximity Read ↗

Clinical characteristics and molecular etiology of partial 17α-hydroxylase deficiency diagnosed in 46,XX patients.Semantic proximity Read ↗

Clinical and molecular manifestation of fifteen 17OHD patients: a novel mutation and a founder effect.Semantic proximity Read ↗

CYP17A1 gene mutations and hypertension variations found in 46, XY females with combined 17α-hydroxylase/17, 20-lyase deficiency.Semantic proximity Read ↗

Phenotype-genotype correlation in eight Chinese 17alpha-hydroxylase/17,20 lyase-deficiency patients with five novel mutations of CYP17A1 gene.Semantic proximity Read ↗

Revealing a New Homozygous Variant in CYP17A1 c.908G>A (p. Gly303Asp) by Genotyping a Chinese Patient with 46, XY 17a-Hydroxylase/17,20-Lyase Deficiency and Adrenal Space-Occupying Lesion.Semantic proximity Read ↗

Association of CYP17A1 Genetic Polymorphisms and Susceptibility to Essential Hypertension in the Southwest Han Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.