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Article

Systematic Pan-Cancer Analysis of KLRB1 with Prognostic Value and Immunological Activity across Human Tumors.

Journal of immunology research - 1 Jan 2022

Cheng Xin, Cao Yucheng, Wang Xiaowei, Cheng Lin, Liu Yaqiong, Lei Jun, Peng Weijun, Shi Dazun

Abstract excerpt

INTRODUCTION: KLRB1 is a gene encoding CD161 expressed in NK cells and some T cell subsets. At present, KLRB1 is believed to affect tumorigenesis and development by regulating the cytotoxicity of NK cells in several cancers. However, there is a lack of systematic reviews of KLRB1 in a variety of malignancies. OBJECTIVES: Hence, our research is aimed at providing a relatively comprehensive understanding of the...

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Identifiers

PMID: 35028320
DOI: 10.1155/2022/5254911
PMCID: PMC8749375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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