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Article

Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation.

Journal of neurodevelopmental disorders - 14 Jan 2022

Klusek Jessica, Fairchild Amanda, Moser Carly, Mailick Marsha R, Thurman Angela John, Abbeduto Leonard

Abstract excerpt

BACKGROUND: Women who carry a premutation allele of the FMR1 gene are at increased vulnerability to an array of age-related symptoms and disorders, including age-related decline in select cognitive skills. However, the risk factors for age-related decline are poorly understood, including the potential role of family history and genetic factors. In other forms of pathological aging, early decline in syntactic...

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Identifiers

PMID: 35026985
DOI: 10.1186/s11689-022-09415-3
PMCID: PMC8903682

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