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Article

Impact of Motile Ciliopathies on Human Development and Clinical Consequences in the Newborn

31 Dec 2021

Abstract excerpt

Motile cilia are hairlike organelles that project outward from a tissue-restricted subset of cells to direct fluid flow. During human development motile cilia guide determination of the left-right axis in the embryo, and in the fetal and neonatal periods they have essential roles in airway clearance in the respiratory tract and regulating cerebral spinal fluid flow in the brain. Dysregulation of motile cilia is...

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PMID: 35011687
DOI: 10.3390/cells11010125

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