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Circulating Placental Alkaline Phosphatase Expressing Exosomes in Maternal Blood Showed Temporal Regulation of Placental Genes

24 Dec 2021

Abstract excerpt

Background:Analysis of placental genes could unravel maternal-fetal complications. However, inaccessibility to placental tissue during early pregnancy has limited this effort. We tested if exosomes (Exo) released by human placenta in the maternal circulation harbor crucial placental genes. Methods:Placental alkaline phosphate positive exosomes (ExoPLAP) were enriched from maternal blood collected at the following...

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PMID: 35004728
DOI: 10.3389/fmed.2021.758971

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