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Epithelial–mesenchymal transition related genes in unruptured aneurysms identified through weighted gene coexpression network analysis

7 Jan 2022

Abstract excerpt

Intracranial aneurysm (IA) can cause fatal subarachnoid hemorrhage (SAH) after rupture, and identifying patients with unruptured IAs is essential for reducing SAH fatalities. The epithelial-mesenchymal transition (EMT) may be vital to IA progression. Here, identified key EMT-related genes in aneurysms and their pathogenic mechanisms via bioinformatic analysis. The GSE13353, GSE75436, and GSE54083 datasets from...

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PMID: 34997174
DOI: 10.1038/s41598-021-04390-6

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