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Late‐life physical activity relates to brain tissue synaptic integrity markers in older adults

7 Jan 2022

Abstract excerpt

INTRODUCTION: Physical activity (PA) is widely recommended for age-related brain health, yet its neurobiology is not well understood. Animal models indicate PA is synaptogenic. We examined the relationship between PA and synaptic integrity markers in older adults. METHODS: Four hundred four decedents from the Rush Memory and Aging Project completed annual actigraphy monitoring (Mean visits = 3.5±2.4) and post...

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PMID: 34994517
DOI: 10.1002/alz.12530

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