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Val109Asp Polymorphism of the Omentin-1 Gene and Incidence of Knee Osteoarthritis in a Chinese Han Population: A Correlation Analysis.

Drug design, development and therapy - 1 Jan 2021

Chen Ruofei, Zhang Yaqin, Xu Honggang, Hu Huaqing, Chen Mingwei, Shuai Zongwen

Abstract excerpt

OBJECTIVE: To investigate the correlation of the Val109Asp polymorphism of the omentin-1 gene with the risk and severity of knee osteoarthritis (KOA) in a Chinese Han population. METHODS: This study enrolled 383 patients with primary KOA and 460 healthy controls. The genotypes were determined by the detection of single nucleotide polymorphism. To explore the interaction between omentin-1 gene polymorphism and...

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PMID: 34992344
DOI: 10.2147/DDDT.S340410
PMCID: PMC8710085

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