Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The m6A methyltransferase METTL3 affects autophagy and progression of nasopharyngeal carcinoma by regulating the stability of lncRNA ZFAS1

3 Jan 2022

Abstract excerpt

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the epithelial cells of the nasopharyngeal mucosa of the head and neck. The role of long non-coding RNA and RNA methylation in NPC has received increasing attention. Therefore, this study aims to investigate the mechanism of lncRNA ZFAS1 in NPC and its relationship with RNA methylation, providing evidence for targeted therapy of NPC....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer-related molecular mechanisms research
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34980191
DOI: 10.1186/s13027-021-00411-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The m6A methyltransferase METTL3 affects autophagy and progression of nasopharyngeal carcinoma by regulating the stability of lncRNA ZFAS1PMID 34980191Read ↗

Gene Signatures and Prognostic Values of m6A Genes in Nasopharyngeal CarcinomaSemantic proximity Read ↗

m6A Demethylase FTO regulates nasopharyngeal carcinoma invasion, migrationSemantic proximity Read ↗

LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitroSemantic proximity Read ↗

VIRMA Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Upregulation of E2F7 in an m6A-Dependent MannerSemantic proximity Read ↗

m5C and m6A modification of long noncoding NKILA accelerates cholangiocarcinoma progression via the miR‐582‐3p‐YAP1 axisSemantic proximity Read ↗

N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decaySemantic proximity Read ↗

The Multifaceted Role of Autophagy in Nasopharyngeal Carcinoma: Translational Perspectives on Pathogenesis, Biomarkers, Treatment Resistance, and Emerging TherapiesSemantic proximity Read ↗

MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma.Semantic proximity Read ↗

ZFAS1 Exerts an Oncogenic Role via Suppressing miR-647 in an m6A-Dependent Manner in Cervical CancerSemantic proximity Read ↗

The comprehensive analysis of the prognostic and functional role of N-terminal methyltransferases 1 in pan-cancerSemantic proximity Read ↗

Emerging roles of lncRNA in Nasopharyngeal Carcinoma and therapeutic opportunitiesSemantic proximity Read ↗

Systematic integration of m6A regulators and autophagy-related genes in combination with long non-coding RNAs predicts survival in glioblastoma multiformeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.