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Article

ELK1 Promotes Epithelial‐Mesenchymal Transition and the Progression of Lung Adenocarcinoma by Upregulating B7‐H3

1 Jan 2021

Abstract excerpt

In previous studies, we found that B7 homolog 3 (B7‐H3) was highly expressed in lung adenocarcinoma (LUAD) and promoted epithelial‐to‐mesenchymal transition (EMT) of LUAD cells. However, the underlying molecular mechanism is unclear. This study is aimed at evaluating the role of Ets‐like protein 1 (ELK1) as a transcriptional regulator of B7‐H3 for mediating the development and progression of LUAD in vitro and in...

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Identifiers

PMID: 34970415
DOI: 10.1155/2021/2805576

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