Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GCM2Variants in Familial and Multiglandular Primary Hyperparathyroidism

30 Dec 2021

Abstract excerpt

CONTEXT: Multiglandular and familial parathyroid disease constitute important fractions of primary hyperparathyroidism (PHPT). Germline missense variants of GCM2, a regulator of parathyroid development, were observed in familial isolated hyperparathyroidism and sporadic PHPT. However, as these previously reported GCM2 variants occur at relatively high frequencies in the population, understanding their potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatological and Skeletal Disorders
Share to Parathyroid Disorders and Treatments
Share to Thyroid and Parathyroid Surgery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34967908
DOI: 10.1210/clinem/dgab929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GCM2Variants in Familial and Multiglandular Primary HyperparathyroidismPMID 34967908Read ↗

Ethnicity of Patients With Germline GCM2-Activating Variants and Primary HyperparathyroidismSemantic proximity Read ↗

Analysis of the GCM2 gene in isolated hypoparathyroidism: a molecular and biochemical study.Semantic proximity Read ↗

GCM2-Activating Mutations in Familial Isolated Hyperparathyroidism.Semantic proximity Read ↗

Familial isolated primary hyperparathyroidism associated with germline GCM2 mutations is more aggressive and has a lesser rate of biochemical cureSemantic proximity Read ↗

Analysis of Activating GCM2 Sequence Variants in Sporadic Parathyroid AdenomasSemantic proximity Read ↗

Germline GCM2 Mutation Screening in Chinese Primary Hyperparathyroidism Patients.Semantic proximity Read ↗

Specifying the molecular pattern of sporadic parathyroid tumorigenesis-The Y282D variant of the GCM2 gene.Semantic proximity Read ↗

Increased prevalence of the GCM2 polymorphism, Y282D, in primary hyperparathyroidism: analysis of three Italian cohorts.Semantic proximity Read ↗

Novel Glial Cells Missing-2 (GCM2) variants in parathyroid disorders.Semantic proximity Read ↗

Germline Mutations Related to Primary Hyperparathyroidism Identified by Next-Generation SequencingSemantic proximity Read ↗

GCM2 p.Tyr394Ser variant in Ashkenazi Israeli patients with suspected familial isolated hyperparathyroidism.Semantic proximity Read ↗

Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.