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Article

Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma

10 Dec 2021

Abstract excerpt

Purposes: Recent studies have suggested that loss-of-function mutations of the tunica intima endothelial receptor tyrosine kinase (TEK) are responsible for approximately 5% of primary congenital glaucoma (PCG) cases in diverse populations. However, the causative role of TEK mutations has not been studied in Chinese PCG patients. Here, we report the mutation spectrum of TEK after screening a large cohort of PCG...

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PMID: 34956319
DOI: 10.3389/fgene.2021.764509

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