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Article

Insertional mutagenesis in Chlamydomonas reinhardtii: An effective strategy for the identification of new genes involved in the DNA damage response.

European journal of protistology - 1 Feb 2022

Gahurová Dominika, Krajčiová Daniela, Reichwalderová Katarína, Slaninová Miroslava

Abstract excerpt

The formation of double-strand breaks in DNA represents a serious stress for all types of organisms and requires a precisely regulated and organized DNA damage response (DDR) to maintain genetic information and genome integrity. Chlamydomonas reinhardtii possesses the characteristics of both plants and animals and is therefore suitable for the identification of novel genes connected to a wide spectrum of...

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PMID: 34954500
DOI: 10.1016/j.ejop.2021.125855

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