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HDAC6 Inhibition Extinguishes Autophagy in Cancer: Recent Insights

14 Dec 2021

Abstract excerpt

Autophagy is an essential intracellular catabolic mechanism involved in the degradation and recycling of damaged organelles regulating cellular homeostasis and energy metabolism. Its activation enhances cellular tolerance to various stresses and is known to be involved in drug resistance. In cancer, autophagy has a dual role in either promoting or blocking tumorigenesis, and recent studies indicate that...

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Share to Autophagy in Disease and Therapy
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PMID: 34944907
DOI: 10.3390/cancers13246280

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