Article
Determination of the relationship between class IV sirtuin genes and growth traits in Chinese black Tibetan sheep.
Animal biotechnology - 1 Nov 2023
Ma Boyan, Khan Rajwali, Raza Sayed Haidar Abbas, Gao Zhanhong, Hou Shengzhen, Ullah Farman, Hassan Montaser M, Hassan Mohamed M, AlGabbani Qwait, Alotaibi Mashael Alhumaidi, Shah Mujahid Ali, Gui Linsheng
Abstract excerpt
Class IV sirtuin (SIRT6 and SIRT7) played essential roles in biometabolism processes via deacetylating specific transcription factors. The present study was conducted to search for mutations in SIRT6/7 and determine their associations with growth traits in black Tibetan sheep. Via DNA sequencing methods, three single-nucleotide polymorphisms (SNPs) were identified in 427 ewes, including a mutation (g.3724C > T)...
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