Article
Linkage of Whole Genome Sequencing, Epidemiological, and Clinical Data to Understand the Genetic Diversity and Clinical Outcomes of Shigella flexneri among Men Who Have Sex with Men in England.
Microbiology spectrum - 22 Dec 2021
Mitchell Holly D, Thomson Nicholas R, Jenkins Claire, Dallman Timothy J, Painset Anaïs, Kirwan Peter, Delpech Valerie, Mikhail Amy F W, Field Nigel, Hughes Gwenda
Abstract excerpt
The public health value of whole genome sequencing (WGS) for Shigella spp. in England has been limited by a lack of information on sexual identity and behavior. We combined WGS data with other data sources to better understand Shigella flexneri transmission in men who have sex with men (MSM). WGS data for all S. flexneri isolates referred to the national reference laboratory were linked to i) clinical and...
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