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Article

The mining and construction of a knowledge base for gene-disease association in mitochondrial diseases.

Scientific reports - 13 Dec 2021

Wang Wei, Song Junying, Chuai Yunhai, Chen Fu, Song Chunlan, Shu Mingming, Wang Yayun, Li Yunfei, Zhai Xinyu, Han Shujie, Yao Shun, Shen Kexin, Shang Wei, Zhang Lei

Abstract excerpt

Mitochondrial diseases are a group of heterogeneous genetic metabolic diseases caused by mitochondrial DNA (mtDNA) or nuclear DNA (nDNA) gene mutations. Mining the gene-disease association of mitochondrial diseases is helpful for understanding the pathogenesis of mitochondrial diseases, for carrying out early clinical diagnosis for related diseases, and for formulating better treatment strategies for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34903783
DOI: 10.1038/s41598-021-03249-0
PMCID: PMC8668972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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