Article
pmrCAB Recombination Events among Colistin-Susceptible and -Resistant Acinetobacter baumannii Clinical Isolates Belonging to International Clone 7.
mSphere - 22 Dec 2021
Nodari Carolina Silva, Fuchs Sebastian Alexander, Xanthopoulou Kyriaki, Cayô Rodrigo, Seifert Harald, Gales Ana Cristina, Dilthey Alexander, Higgins Paul G
Abstract excerpt
Acinetobacter baumannii is a successful nosocomial pathogen due to its genomic plasticity. Homologous recombination allows genetic exchange and allelic variation among different clonal lineages and is one of the mechanisms associated with horizontal gene transfer (HGT) of resistance determinants. The main mechanism of colistin resistance in A. baumannii is mediated through mutations in the pmrCAB operon. Here, we...
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