Article
Family History of Breast Cancer Is Associated with Elevated Risk of Prostate Cancer: Evidence for Shared Genetic Risks.
Human heredity - 1 Jan 2022
Calvo Chozas Adrián, Mahjani Behrang, Rönnegård Lars
Abstract excerpt
INTRODUCTION: Although breast and prostate cancers arise in different organs and are more frequent in the opposite sex, multiple studies have reported an association between their family history. Analysis of single nucleotide polymorphism data, based on distant relatives, has revealed a small positive genetic correlation between these cancers explained by common variants. The estimate of genetic correlation based...
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