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Intestinal microbial communities and Holdemanella isolated from HIV+/− men who have sex with men increase frequencies of lamina propria CCR5 + CD4 + T cells

1 Jan 2021

Abstract excerpt

Men who have sex with men (MSM), regardless of HIV infection status, have an intestinal microbiome that is compositionally distinct from men who have sex with women (MSW) and women. We recently showed HIV-negative MSM have elevated levels of intestinal CD4+ T cells expressing CCR5, a critical co-receptor for HIV. Whether elevated expression of CCR5 is driven by the altered gut microbiome composition in MSM has...

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PMID: 34818131
DOI: 10.1080/19490976.2021.1997292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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