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Article

TNF-α Regulated Endometrial Stroma Secretome Promotes Trophoblast Invasion

1 Nov 2021

Abstract excerpt

Successful implantation requires the coordinated migration and invasion of trophoblast cells from out of the blastocyst and into the endometrium. This process relies on signals produced by cells in the maternal endometrium. However, the relative contribution of stroma cells remains unclear. The study of human implantation has major technical limitations, therefore the need of in vitro models to elucidate the...

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PMID: 34790194
DOI: 10.3389/fimmu.2021.737401

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