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Article

Blood eosinophils in managing preschool wheeze: Lessons learnt from a proof-of-concept trial.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jan 2022

Saglani Sejal, Bingham Yvonne, Balfour-Lynn Ian, Goldring Stephen, Gupta Atul, Banya Winston, Moreiras John, Fleming Louise, Bush Andrew, Rosenthal Mark

Abstract excerpt

BACKGROUND: Management of preschool wheeze is based predominantly on symptom patterns. OBJECTIVE: To determine whether personalizing therapy using blood eosinophils or airway bacterial infection results in fewer attacks compared with standard care. METHODS: A proof-of-concept, randomized trial to investigate whether the prescription of inhaled corticosteroids (ICS) guided by blood eosinophils, or targeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34783100
DOI: 10.1111/pai.13697

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