Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non-Small-Cell Lung Cancer With EGFR Mutation (IMPACT).

doi:10.1200/JCO.21.01729

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Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non-Small-Cell Lung Cancer With EGFR Mutation (IMPACT).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jan 2022

Tada Hirohito, Mitsudomi Tetsuya, Misumi Toshihiro, Sugio Kenji, Tsuboi Masahiro, Okamoto Isamu, Iwamoto Yasuo, Sakakura Noriaki, Sugawara Shunichi, Atagi Shinji, Takahashi Toshiaki, Hayashi Hidetoshi, Okada Morihito, Inokawa Hidetoshi, Yoshioka Hiroshige, Takahashi Kazuhisa, Higashiyama Masahiko, Yoshino Ichiro, Nakagawa Kazuhiko

Abstract excerpt

PURPOSE: To investigate the efficacy of gefitinib as an adjuvant therapy for non-small-cell lung cancer patients with EGFR mutation. PATIENTS AND METHODS: IMPACT (WJOG6410L; University Hospital Medical Information Network Clinical Trials Registry: UMIN000006252), a randomized, open-label, phase III study, included patients with completely resected pathologic stage II-III non-small-cell lung cancer harboring EGFR...

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PMID: 34726958
DOI: 10.1200/JCO.21.01729

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