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Plasmepsin-like Aspartyl Proteases in Babesia

26 Sept 2021

Abstract excerpt

Apicomplexan genomes encode multiple pepsin-family aspartyl proteases (APs) that phylogenetically cluster to six independent clades (A to F). Such diversification has been powered by the function-driven evolution of the ancestral apicomplexan AP gene and is associated with the adaptation of various apicomplexan species to different strategies of host infection and transmission through various invertebrate...

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PMID: 34684190
DOI: 10.3390/pathogens10101241

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