Article
Structural Protein Analysis of Driver Gene Mutations in Conjunctival Melanoma.
Genes - 15 Oct 2021
Djulbegovic Mak B, Uversky Vladimir N, Harbour J William, Galor Anat, Karp Carol L
Abstract excerpt
In recent years, there has been tremendous enthusiasm with respect to detailing the genetic basis of many neoplasms, including conjunctival melanoma (CM). We aim to analyze five proteins associated with CM, namely BRAF, NRAS, c-KIT, NF1, and PTEN. We evaluated each protein for its intrinsically disordered protein regions (IDPRs) and its protein-protein interactions (PPI) with the Predictor of Natural Disordered...
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