Article
[Targeted therapies with BRAF inhibitors for pediatric low- and high-grade gliomas with BRAFv600e mutation. Prof. Dr. Juan P. Garrahan Hospital experience].
Medicina - 1 Jan 2021
Warriner Eric, Fernández Ponce Nicolás, Freytes Candela, Sampor Claudia, Oller Agustina, Rugilo Carlos, Lubieniecki Fabiana, Vazquez Valeria, Alderete Daniel, Baroni Lorena V
Abstract excerpt
The BRAFV600E point mutation plays a key role in the tumorigenesis of many gliomas. Inhibiting its product is part of the innovative therapies emerging in recent years. Knowing the role of these treatments is essential. The aim of this experience was to describe the clinical-radiological response of pediatric BRAFV600E mutated gliomas treated with BRAF inhibitors. To this end, a descriptive and retrospective...
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