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Insulin gene mutations linked to permanent neonatal diabetes mellitus in Indian population.

Journal of diabetes and its complications - 1 Dec 2021

Gopi Sundaramoorthy, Gowri Palanisamy, Panda Jayant Kumar, Sathyanarayana Santhosh Olety, Gupta Sunil, Chandru Sundaramoorthy, Chandni Radhakrishnan, Raghupathy Palany, Dayal Devi, Mohan Viswanathan, Radha Venkatesan

Abstract excerpt

BACKGROUND AND AIM: Neonatal diabetes mellitus (NDM) is a rare monogenic disorder of pancreatic beta cell mass and/or function. In the present study we aimed to evaluate the INS gene mutations in a cohort of children with Permanent Neonatal Diabetes Mellitus (PNDM) and to explore the clinical and genetic characteristics of PNDM caused by INS mutations. METHODS: Direct sequencing of all exons of INS genes was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34593315
DOI: 10.1016/j.jdiacomp.2021.108022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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