Article
Frequencies of glyoxalase I phenotypes as biological markers in chronic alcoholism.
Alcohol (Fayetteville, N.Y.) - 1 Jan 2000
Ledig M, Doffoel M, Ziessel M, Kopp P, Charrault A, Tongio M M, Mayer S, Bockel R, Mandel P
Abstract excerpt
Biological markers for alcoholism would be a valuable tool for early diagnosis. We have studied the phenotype frequencies of genetically determined erythrocyte enzymes in 397 alcoholics, including two populations with liver disease: steatosis (n = 86) and cirrhosis (n = 128) and a population of alcoholics without apparent liver disease (n = 183) compared to a well selected control population (n = 177). Only for...
Topics
- Alcoholism
- Erythrocytes
- Female
- Genetic Markers
- Humans
- Isoenzymes
- Lactoylglutathione Lyase
- Lyases
- Male
- Phenotype