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Article

The Pathogenic and Therapeutic Implications of Ceramide Abnormalities in Atopic Dermatitis

10 Sept 2021

Abstract excerpt

Ceramides play an essential role in forming a permeability barrier in the skin. Atopic dermatitis (AD) is a common chronic skin disease associated with skin barrier dysfunction and immunological abnormalities. In patients with AD, the amount and composition of ceramides in the stratum corneum are altered. This suggests that ceramide abnormalities are involved in the pathogenesis of AD. The mechanism underlying...

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PMID: 34572035
DOI: 10.3390/cells10092386

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