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Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

27 Sept 2021

Abstract excerpt

Understanding relationships between spontaneous cancer in companion (pet) canines and humans can facilitate biomarker and drug development in both species. Towards this end we developed an experimental-bioinformatic protocol that analyzes canine transcriptomics data in the context of existing human data to evaluate comparative relevance of canine to human cancer. We used this protocol to characterize five canine...

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PMID: 34570764
DOI: 10.1371/journal.pcbi.1009450

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