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Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients

21 Sept 2021

Abstract excerpt

Mycobacterium (M.) abscessus infections in Cystic Fibrosis (CF) patients cause a deterioration of lung function. Treatment of these multidrug-resistant pathogens is associated with severe side-effects, while frequently unsuccessful. Insight on M. abscessus genomic evolvement during chronic lung infection would be beneficial for improving treatment strategies. A longitudinal study enrolling 42 CF patients was...

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PMID: 34546836
DOI: 10.1080/21505594.2021.1959808

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