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Article

Juvenile hormone signaling promotes ovulation and maintains egg shape by inducing expression of extracellular matrix genes.

Proceedings of the National Academy of Sciences of the United States of America - 28 Sept 2021

Luo Wei, Liu Suning, Zhang Wenqiang, Yang Liu, Huang Jianhua, Zhou Shutang, Feng Qili, Palli Subba Reddy, Wang Jian, Roth Siegfried, Li Sheng

Abstract excerpt

It is well documented that the juvenile hormone (JH) can function as a gonadotropic hormone that stimulates vitellogenesis by activating the production and uptake of vitellogenin in insects. Here, we describe a phenotype associated with mutations in the Drosophila JH receptor genes, Met and Gce: the accumulation of mature eggs with reduced egg length in the ovary. JH signaling is mainly activated in ovarian...

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Identifiers

PMID: 34544864
DOI: 10.1073/pnas.2104461118
PMCID: PMC8488625

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