Article
Molecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early-Stage Non-Squamous Non-Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit From Adjuvant Chemotherapy.
Clinical lung cancer - 1 Nov 2021
Woodard Gavitt A, Kratz Johannes R, Haro Greg, Gubens Matthew A, Blakely Collin M, Jones Kirk D, Mann Michael J, Jablons David M
Abstract excerpt
BACKGROUND: A clinically-certified gene expression profile improved survival in a cohort of stage I-IIA NSCLC patients by identifying those likely to benefit from adjuvant intervention. EGFR mutation status has not provided this type of predictive risk discrimination in stage IA NSCLC, and overtreatment of low-risk stage IB patients may have limited the overall benefit seen recently in the adjuvant application of...
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