Article
Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study.
Progress in neuro-psychopharmacology & biological psychiatry - 8 Mar 2022
Fusar-Poli Laura, Pries Lotta-Katrin, van Os Jim, Erzin Gamze, Delespaul Philippe, Kenis Gunter, Luykx Juryen J, Lin Bochao D, Richards Alexander L, Akdede Berna, Binbay Tolga, Altınyazar Vesile, Yalınçetin Berna, Gümüş-Akay Güvem, Cihan Burçin, Soygür Haldun, Ulaş Halis, Cankurtaran Eylem Şahin, Kaymak Semra Ulusoy, Mihaljevic Marina M, Andric-Petrovic Sanja, Mirjanic Tijana, Bernardo Miguel, Mezquida Gisela, Amoretti Silvia, Bobes Julio, Saiz Pilar A, García-Portilla Maria Paz, Sanjuan Julio, Aguilar Eduardo J, Santos José Luis, Jiménez-López Estela, Arrojo Manuel, Carracedo Angel, López Gonzalo, González-Peñas Javier, Parellada Mara, Maric Nadja P, Atbaşoğlu Cem, Üçok Alp, Alptekin Köksal, Saka Meram Can, Aguglia Eugenio, Arango Celso, O'Donovan Michael, Rutten Bart P F, Guloksuz Sinan
Abstract excerpt
BACKGROUND: Social cognition impairments, such as facial emotion recognition (FER), have been acknowledged since the earliest description of schizophrenia. Here, we tested FER as an intermediate phenotype for psychosis using two approaches that are indicators of genetic risk for schizophrenia: the proxy-genetic risk approach (family design) and the polygenic risk score for schizophrenia (PRS-SCZ). METHODS: The...
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